Aldehyde dehydrogenase, dimeric NADP-preferring · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P30838. Use UniProt P30838 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P30838 as the stable identity anchor, then attach disease evidence before program review.
Aldehyde dehydrogenase, dimeric NADP-preferring
Review this target as Aldehyde dehydrogenase, dimeric NADP-preferring, mapped to UniProt P30838. Sequence length is 453 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Aldehyde dehydrogenase, dimeric NADP-preferring as ChEMBL target CHEMBL3578, mapped to UniProt P30838. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Aldehyde dehydrogenase, dimeric NADP-preferring |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P30838 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Aldehyde dehydrogenase, dimeric NADP-preferring |
| UniProt Accession | P30838 |
| Component Type | Protein |
| Sequence Length | 453 aa |
Aldehyde dehydrogenase, dimeric NADP-preferring
Review this target as Aldehyde dehydrogenase, dimeric NADP-preferring, mapped to UniProt P30838. Sequence length is 453 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1378094 | 7.09 | Ki | 82.0 | Preclinical |
| CHEMBL4745360 | 6.71 | IC50 | 193.0 | Preclinical |
| CHEMBL1378094 | 6.7 | IC50 | 200.0 | Preclinical |
| CHEMBL4754311 | 6.66 | IC50 | 219.0 | Preclinical |
| CHEMBL4777582 | 6.66 | IC50 | 219.0 | Preclinical |
| CHEMBL4753971 | 6.62 | IC50 | 241.0 | Preclinical |
| CHEMBL5076191 | 6.62 | Ki | 240.0 | Preclinical |
| CHEMBL4755837 | 6.61 | IC50 | 246.0 | Preclinical |
| CHEMBL4791741 | 6.61 | IC50 | 246.0 | Preclinical |
| CHEMBL4763602 | 6.6 | IC50 | 251.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 23 | 81 | 5.6 |
| cell-based format | 10 | 0 | — |
| assay format | 5 | 22 | 5.7 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 4 | 0 | — |