Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt Q64578. Use UniProt Q64578 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q64578 as the stable identity anchor, then attach disease evidence before program review.
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
Review this target as Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, mapped to UniProt Q64578. Sequence length is 994 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 as ChEMBL target CHEMBL3585236, mapped to UniProt Q64578. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | Q64578 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 |
| UniProt Accession | Q64578 |
| Component Type | Protein |
| Sequence Length | 994 aa |
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
Review this target as Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, mapped to UniProt Q64578. Sequence length is 994 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4637788 | 4.74 | IC50 | 18170.0 | Preclinical |
| CHEMBL4648427 | 4.74 | IC50 | 18220.0 | Preclinical |
| CHEMBL4173326 | 4.54 | IC50 | 28650.0 | Preclinical |
| CHEMBL464006 | 4.54 | IC50 | 28650.0 | Preclinical |
| CHEMBL1096940 | 4.19 | IC50 | 64820.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 5 | 7 | 4.5 |
| assay format | 1 | 0 | — |
| single protein format | 1 | 0 | — |