Dihydroorotate dehydrogenase (quinone), mitochondrial · SINGLE PROTEIN · Plasmodium falciparum (isolate 3D7)
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As of 2026-09-14Protein identity stays anchored to UniProt Q08210. Use UniProt Q08210 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q08210 as the stable identity anchor, then attach disease evidence before program review.
Dihydroorotate dehydrogenase (quinone), mitochondrial
Review this target as Dihydroorotate dehydrogenase (quinone), mitochondrial, mapped to UniProt Q08210. Sequence length is 569 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Dihydroorotate dehydrogenase (quinone), mitochondrial as ChEMBL target CHEMBL3588732, mapped to UniProt Q08210. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Dihydroorotate dehydrogenase (quinone), mitochondrial |
| Target Type | SINGLE PROTEIN |
| Organism | Plasmodium falciparum (isolate 3D7) |
| UniProt | Q08210 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Dihydroorotate dehydrogenase (quinone), mitochondrial |
| UniProt Accession | Q08210 |
| Component Type | Protein |
| Sequence Length | 569 aa |
Dihydroorotate dehydrogenase (quinone), mitochondrial
Review this target as Dihydroorotate dehydrogenase (quinone), mitochondrial, mapped to UniProt Q08210. Sequence length is 569 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4636879 | 7.75 | IC50 | 18.0 | Preclinical |
| CHEMBL3289671 | 7.7 | IC50 | 20.0 | Preclinical |
| CHEMBL4633246 | 7.7 | IC50 | 20.0 | Preclinical |
| CHEMBL3289672 | 7.66 | IC50 | 22.0 | Preclinical |
| CHEMBL1956283 | 7.55 | IC50 | 28.0 | Preclinical |
| CHEMBL1784578 | 7.5 | IC50 | 32.0 | Preclinical |
| CHEMBL1956290 | 7.46 | IC50 | 35.0 | Preclinical |
| CHEMBL3289670 | 7.46 | IC50 | 35.0 | Preclinical |
| CHEMBL1738786 | 7.42 | IC50 | 38.0 | Preclinical |
| CHEMBL3689083 | 7.37 | IC50 | 43.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 11 | 3 | 4.8 |
| single protein format | 8 | 51 | 6.6 |