CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q11201. Use UniProt Q11201 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q11201 as the stable identity anchor, then attach disease evidence before program review.
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1
Review this target as CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1, mapped to UniProt Q11201. Sequence length is 340 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 as ChEMBL target CHEMBL3596074, mapped to UniProt Q11201. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q11201 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 |
| UniProt Accession | Q11201 |
| Component Type | Protein |
| Sequence Length | 340 aa |
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1
Review this target as CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1, mapped to UniProt Q11201. Sequence length is 340 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3596261 | 6.06 | IC50 | 880.0 | Preclinical |
| CHEMBL3596256 | 5.96 | Ki | 1100.0 | Preclinical |
| CHEMBL3596260 | 5.66 | Ki | 2200.0 | Preclinical |
| CHEMBL3596260 | 5.3 | IC50 | 5000.0 | Preclinical |
| CHEMBL1170899 | 5.17 | IC50 | 6700.0 | Preclinical |
| CHEMBL5641631 | 4.89 | IC50 | 13000.0 | Preclinical |
| CHEMBL1478 | 4.68 | IC50 | 21000.0 | Preclinical |
| CHEMBL1170697 | 4.52 | IC50 | 30200.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 3 | 7 | 5.2 |
| cell-based format | 1 | 1 | 6.0 |