2-acylglycerol O-acyltransferase 2 · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt Q80W94. Use UniProt Q80W94 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q80W94 as the stable identity anchor, then attach disease evidence before program review.
2-acylglycerol O-acyltransferase 2
Review this target as 2-acylglycerol O-acyltransferase 2, mapped to UniProt Q80W94. Sequence length is 334 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats 2-acylglycerol O-acyltransferase 2 as ChEMBL target CHEMBL3603729, mapped to UniProt Q80W94. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether 2-acylglycerol O-acyltransferase 2 is the right protein anchor across sources, using UniProt Q80W94 as the stable mapping.
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| Preferred Name | 2-acylglycerol O-acyltransferase 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | Q80W94 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | 2-acylglycerol O-acyltransferase 2 |
| UniProt Accession | Q80W94 |
| Component Type | Protein |
| Sequence Length | 334 aa |
2-acylglycerol O-acyltransferase 2
Review this target as 2-acylglycerol O-acyltransferase 2, mapped to UniProt Q80W94. Sequence length is 334 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5686988 | 8.96 | IC50 | 1.1 | Preclinical |
| CHEMBL5687022 | 8.72 | IC50 | 1.9 | Preclinical |
| CHEMBL4455357 | 8.62 | IC50 | 2.4 | Preclinical |
| CHEMBL5415437 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL5424834 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL5406388 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL5435045 | 8.22 | IC50 | 6.0 | Preclinical |
| CHEMBL5414175 | 8.15 | IC50 | 7.0 | Preclinical |
| CHEMBL5401316 | 8.1 | IC50 | 8.0 | Preclinical |
| CHEMBL5423735 | 8.0 | IC50 | 10.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 2 | 30 | 7.5 |
| cell membrane format | 1 | 3 | 8.8 |