Use UniProt P63319 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL3604 Target Snapshot
Protein kinase C gamma type · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-13Protein identity stays anchored to UniProt P63319. Use UniProt P63319 as the stable identity anchor, then attach disease evidence before program review.
Protein kinase C gamma type
Review this target as Protein kinase C gamma type, mapped to UniProt P63319. Sequence length is 697 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Protein kinase C gamma type as ChEMBL target CHEMBL3604, mapped to UniProt P63319. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Protein kinase C gamma type is the right protein anchor across sources, using UniProt P63319 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Protein kinase C gamma type |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P63319 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Protein kinase C gamma type |
| UniProt Accession | P63319 |
| Component Type | Protein |
| Sequence Length | 697 aa |
Protein kinase C gamma type
How to read this target
Review this target as Protein kinase C gamma type, mapped to UniProt P63319. Sequence length is 697 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL417692 | 8.7 | Ki | 2.0 | Preclinical |
| CHEMBL538718 | 8.27 | IC50 | 5.4 | Preclinical |
| CHEMBL388978 | 8.05 | IC50 | 9.0 | Preclinical |
| CHEMBL26501 | 7.44 | IC50 | 36.5 | Preclinical |
| CHEMBL27768 | 7.28 | Ki | 52.9 | Preclinical |
| CHEMBL51758 | 6.96 | IC50 | 110.0 | Preclinical |
| CHEMBL51708 | 6.77 | IC50 | 170.0 | Preclinical |
| CHEMBL53856 | 6.66 | IC50 | 220.0 | Preclinical |
| CHEMBL300479 | 6.55 | IC50 | 280.0 | Preclinical |
| CHEMBL301515 | 6.52 | IC50 | 300.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 8 assays, 75 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 5 | 73 | 5.8 |
| cell-based format | 2 | 0 | — |
| single protein format | 1 | 2 | 7.9 |