Secreted mono- and diacylglycerol lipase LIP1 · SINGLE PROTEIN · Malassezia globosa (strain ATCC MYA-4612 / CBS 7966)(Dandruff-associated fungus)
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As of 2026-09-14Protein identity stays anchored to UniProt A8PUY1. Use UniProt A8PUY1 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt A8PUY1 as the stable identity anchor, then attach disease evidence before program review.
Secreted mono- and diacylglycerol lipase LIP1
Review this target as Secreted mono- and diacylglycerol lipase LIP1, mapped to UniProt A8PUY1. Sequence length is 304 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Secreted mono- and diacylglycerol lipase LIP1 as ChEMBL target CHEMBL3608197, mapped to UniProt A8PUY1. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Secreted mono- and diacylglycerol lipase LIP1 |
| Target Type | SINGLE PROTEIN |
| Organism | Malassezia globosa (strain ATCC MYA-4612 / CBS 7966)(Dandruff-associated fungus) |
| UniProt | A8PUY1 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Secreted mono- and diacylglycerol lipase LIP1 |
| UniProt Accession | A8PUY1 |
| Component Type | Protein |
| Sequence Length | 304 aa |
Secreted mono- and diacylglycerol lipase LIP1
Review this target as Secreted mono- and diacylglycerol lipase LIP1, mapped to UniProt A8PUY1. Sequence length is 304 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3609530 | 6.72 | IC50 | 190.0 | Preclinical |
| CHEMBL3609533 | 4.64 | IC50 | 22860.0 | Preclinical |
| CHEMBL3609534 | 4.2 | IC50 | 63600.0 | Preclinical |
| CHEMBL158897 | 4.12 | IC50 | 75250.0 | Preclinical |
| CHEMBL3609531 | 4.09 | IC50 | 81750.0 | Preclinical |
| CHEMBL3609532 | 4.01 | IC50 | 98340.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 4 | 6 | 4.6 |