Cytochrome P450 11B2, mitochondrial · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt P15539. Use UniProt P15539 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P15539 as the stable identity anchor, then attach disease evidence before program review.
Cytochrome P450 11B2, mitochondrial
Review this target as Cytochrome P450 11B2, mitochondrial, mapped to UniProt P15539. Sequence length is 500 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Cytochrome P450 11B2, mitochondrial as ChEMBL target CHEMBL3621020, mapped to UniProt P15539. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Cytochrome P450 11B2, mitochondrial |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P15539 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Cytochrome P450 11B2, mitochondrial |
| UniProt Accession | P15539 |
| Component Type | Protein |
| Sequence Length | 500 aa |
Cytochrome P450 11B2, mitochondrial
Review this target as Cytochrome P450 11B2, mitochondrial, mapped to UniProt P15539. Sequence length is 500 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4082403 | 9.14 | IC50 | 0.73 | Preclinical |
| CHEMBL4093575 | 7.68 | IC50 | 21.0 | Preclinical |
| CHEMBL5594758 | 7.64 | IC50 | 23.0 | Preclinical |
| CHEMBL4070323 | 6.99 | IC50 | 102.0 | Preclinical |
| CHEMBL5570220 | 6.82 | IC50 | 153.0 | Preclinical |
| CHEMBL4072871 | 6.77 | IC50 | 170.0 | Preclinical |
| CHEMBL9298 | 6.72 | IC50 | 190.0 | Clinical |
| CHEMBL3099695 | 6.68 | IC50 | 210.0 | Approved |
| CHEMBL4088766 | 6.59 | IC50 | 257.0 | Preclinical |
| CHEMBL4099824 | 6.52 | IC50 | 300.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 4 | 32 | 6.3 |