Carbonic anhydrase, alpha family · SINGLE PROTEIN · Thiomicrospira crunogena (strain XCL-2)
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As of 2026-09-14Protein identity stays anchored to UniProt Q31FD6. Use UniProt Q31FD6 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q31FD6 as the stable identity anchor, then attach disease evidence before program review.
carbonic anhydrase
Review this target as Carbonic anhydrase, alpha family, mapped to UniProt Q31FD6. ChEMBL maps the protein component as carbonic anhydrase. Sequence length is 315 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Carbonic anhydrase, alpha family as ChEMBL target CHEMBL3621035, mapped to UniProt Q31FD6. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Carbonic anhydrase, alpha family |
| Target Type | SINGLE PROTEIN |
| Organism | Thiomicrospira crunogena (strain XCL-2) |
| UniProt | Q31FD6 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | carbonic anhydrase |
| UniProt Accession | Q31FD6 |
| Component Type | Protein |
| Sequence Length | 315 aa |
carbonic anhydrase
Review this target as Carbonic anhydrase, alpha family, mapped to UniProt Q31FD6. ChEMBL maps the protein component as carbonic anhydrase. Sequence length is 315 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL360356 | 8.6 | Ki | 2.5 | Preclinical |
| CHEMBL73962 | 8.57 | Ki | 2.7 | Preclinical |
| CHEMBL18 | 8.39 | Ki | 4.1 | Approved |
| CHEMBL220491 | 8.38 | Ki | 4.2 | Approved |
| CHEMBL20 | 8.37 | Ki | 4.3 | Approved |
| CHEMBL6753 | 8.32 | Ki | 4.8 | Preclinical |
| CHEMBL268439 | 8.25 | Ki | 5.6 | Preclinical |
| CHEMBL218490 | 8.15 | Ki | 7.0 | Approved |
| CHEMBL6919 | 7.67 | Ki | 21.2 | Preclinical |
| CHEMBL17 | 7.61 | Ki | 24.8 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 4 | 6.0 |
| single protein format | 1 | 40 | 7.1 |