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Target Snapshot

CHEMBL3632452 Target Snapshot

Mucosa-associated lymphoid tissue lymphoma translocation protein 1 · SINGLE PROTEIN · Homo sapiens

1,222Compounds
114Assays
2Approved Drugs
1,502.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt Q9UDY8. Use UniProt Q9UDY8 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q9UDY8 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Mucosa-associated lymphoid tissue lymphoma translocation protein 1 as ChEMBL target CHEMBL3632452, mapped to UniProt Q9UDY8. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Mucosa-associated lymphoid tissue lymphoma translocation protein 1
SINGLE PROTEIN · Homo sapiens
As of 2026-09-14
ChEMBL target ID
CHEMBL3632452
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
Q9UDY8
Mucosa-associated lymphoid tissue lymphoma translocation protein 1
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Mucosa-associated lymphoid tissue lymphoma translocation protein 1 is the right protein anchor across sources, using UniProt Q9UDY8 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelMucosa-associated lymphoid tissue lymphoma translocation protein 1
UniProt AccessionQ9UDY8
Component TypeProtein
Sequence Length824 aa

Mucosa-associated lymphoid tissue lymphoma translocation protein 1

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Mucosa-associated lymphoid tissue lymphoma translocation protein 1, mapped to UniProt Q9UDY8. Sequence length is 824 aa.

Mapped IDQ9UDY8
Review nameMucosa-associated lymphoid tissue lymphoma translocation protein 1
OrganismHomo sapiens
Clinical Profile

Clinical Phase Distribution

2
Approved
2
Phase II
Assay Mix

Activity Type Distribution

IC501,373.0
KI99.0
EC5030.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL3806279 11.0 IC50 0.01 Preclinical
CHEMBL5918941 11.0 IC50 0.01 Preclinical
CHEMBL6053196 11.0 IC50 0.01 Preclinical
CHEMBL5745794 10.96 IC50 0.011 Preclinical
CHEMBL5958499 10.96 IC50 0.011 Preclinical
CHEMBL5978166 10.96 IC50 0.011 Preclinical
CHEMBL5985777 10.96 IC50 0.011 Preclinical
CHEMBL5837541 10.92 IC50 0.012 Preclinical
CHEMBL5880742 10.92 IC50 0.012 Preclinical
CHEMBL5921519 10.92 IC50 0.012 Preclinical
Distribution

pChEMBL Value Distribution

120
5.0
152
5.5
174
6.0
218
6.5
233
7.0
133
7.5
29
8.0
6
8.5
2
9.0
6
9.5
pChEMBL
Approved Drugs

Approved Drugs

Assay Landscape

Assay Landscape

114
Total Assays
1,197
Tested Compounds
2
Assay Types
Binding — 112 assays, 1,197 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 46 95 6.4
single protein format 34 428 7.6
assay format 22 659 6.5
tissue-based format 6 12 6.4
subcellular format 4 3 5.3
Functional — 2 assays, 2 compounds
BAO Format Assays Compounds Avg pChEMBL
assay format 2 2 7.1

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine