Alpha-1A adrenergic receptor · SINGLE PROTEIN · Oryctolagus cuniculus
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As of 2026-09-13Protein identity stays anchored to UniProt O02824. Use UniProt O02824 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O02824 as the stable identity anchor, then attach disease evidence before program review.
Alpha-1A adrenergic receptor
Review this target as Alpha-1A adrenergic receptor, mapped to UniProt O02824. Sequence length is 466 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Alpha-1A adrenergic receptor as ChEMBL target CHEMBL3637, mapped to UniProt O02824. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Alpha-1A adrenergic receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Oryctolagus cuniculus |
| UniProt | O02824 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Alpha-1A adrenergic receptor |
| UniProt Accession | O02824 |
| Component Type | Protein |
| Sequence Length | 466 aa |
Alpha-1A adrenergic receptor
Review this target as Alpha-1A adrenergic receptor, mapped to UniProt O02824. Sequence length is 466 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL314880 | 10.7 | Kd | 0.01995 | Preclinical |
| CHEMBL330579 | 10.0 | Kd | 0.1 | Preclinical |
| CHEMBL313775 | 10.0 | Kd | 0.1 | Preclinical |
| CHEMBL327231 | 9.9 | Kd | 0.1259 | Preclinical |
| CHEMBL91278 | 9.8 | Kd | 0.1585 | Preclinical |
| CHEMBL836 | 9.8 | Kd | 0.1585 | Approved |
| CHEMBL91400 | 9.7 | Kd | 0.1995 | Preclinical |
| CHEMBL327168 | 9.5 | Kd | 0.3162 | Preclinical |
| CHEMBL88211 | 9.4 | Kd | 0.3981 | Preclinical |
| CHEMBL88160 | 9.3 | Kd | 0.5012 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 5 | 62 | 8.7 |
| tissue-based format | 3 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 4 | 17 | 6.1 |