Gag-Pol polyprotein · SINGLE PROTEIN · Human immunodeficiency virus type 1 group M subtype B (isolateARV2/SF2) (HIV-1)
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As of 2026-09-14Protein identity stays anchored to UniProt P03369. Use UniProt P03369 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P03369 as the stable identity anchor, then attach disease evidence before program review.
Gag-Pol polyprotein
Review this target as Gag-Pol polyprotein, mapped to UniProt P03369. Sequence length is 1437 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Gag-Pol polyprotein as ChEMBL target CHEMBL3638331, mapped to UniProt P03369. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Gag-Pol polyprotein |
| Target Type | SINGLE PROTEIN |
| Organism | Human immunodeficiency virus type 1 group M subtype B (isolateARV2/SF2) (HIV-1) |
| UniProt | P03369 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Gag-Pol polyprotein |
| UniProt Accession | P03369 |
| Component Type | Protein |
| Sequence Length | 1437 aa |
Gag-Pol polyprotein
Review this target as Gag-Pol polyprotein, mapped to UniProt P03369. Sequence length is 1437 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL492254 | 10.59 | Ki | 0.026 | Preclinical |
| CHEMBL523528 | 10.39 | Ki | 0.041 | Preclinical |
| CHEMBL3645123 | 9.96 | Ki | 0.11 | Preclinical |
| CHEMBL467420 | 9.82 | Ki | 0.15 | Preclinical |
| CHEMBL512807 | 9.8 | Ki | 0.16 | Preclinical |
| CHEMBL517126 | 9.8 | Ki | 0.16 | Preclinical |
| CHEMBL3645127 | 9.74 | Ki | 0.18 | Preclinical |
| CHEMBL3645129 | 9.47 | Ki | 0.34 | Preclinical |
| CHEMBL3645124 | 9.4 | Ki | 0.4 | Preclinical |
| CHEMBL3645128 | 9.3 | Ki | 0.5 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 20 | 9.1 |