Membrane metallo-endopeptidase-like 1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q495T6. Use UniProt Q495T6 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q495T6 as the stable identity anchor, then attach disease evidence before program review.
Membrane metallo-endopeptidase-like 1
Review this target as Membrane metallo-endopeptidase-like 1, mapped to UniProt Q495T6. Sequence length is 779 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Membrane metallo-endopeptidase-like 1 as ChEMBL target CHEMBL3638356, mapped to UniProt Q495T6. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Membrane metallo-endopeptidase-like 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q495T6 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Membrane metallo-endopeptidase-like 1 |
| UniProt Accession | Q495T6 |
| Component Type | Protein |
| Sequence Length | 779 aa |
Membrane metallo-endopeptidase-like 1
Review this target as Membrane metallo-endopeptidase-like 1, mapped to UniProt Q495T6. Sequence length is 779 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3703477 | 10.52 | IC50 | 0.03 | Preclinical |
| CHEMBL3676152 | 10.15 | IC50 | 0.07 | Preclinical |
| CHEMBL3703472 | 10.15 | IC50 | 0.07 | Preclinical |
| CHEMBL3703478 | 10.05 | IC50 | 0.09 | Preclinical |
| CHEMBL3676150 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL3703475 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL3703482 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL3703483 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL3677671 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL3703479 | 9.52 | IC50 | 0.3 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 2 | 44 | 8.4 |