Aurora kinase B-B · SINGLE PROTEIN · Xenopus laevis
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As of 2026-09-14Protein identity stays anchored to UniProt Q6GPL3. Use UniProt Q6GPL3 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q6GPL3 as the stable identity anchor, then attach disease evidence before program review.
Aurora kinase B-B
Review this target as Aurora kinase B-B, mapped to UniProt Q6GPL3. Sequence length is 368 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Aurora kinase B-B as ChEMBL target CHEMBL3638361, mapped to UniProt Q6GPL3. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Aurora kinase B-B is the right protein anchor across sources, using UniProt Q6GPL3 as the stable mapping.
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| Preferred Name | Aurora kinase B-B |
| Target Type | SINGLE PROTEIN |
| Organism | Xenopus laevis |
| UniProt | Q6GPL3 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Aurora kinase B-B |
| UniProt Accession | Q6GPL3 |
| Component Type | Protein |
| Sequence Length | 368 aa |
Aurora kinase B-B
Review this target as Aurora kinase B-B, mapped to UniProt Q6GPL3. Sequence length is 368 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3699137 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL3699142 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL3699139 | 8.4 | IC50 | 4.0 | Preclinical |
| CHEMBL3699140 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL3699141 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL3699138 | 8.15 | IC50 | 7.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 6 | 8.4 |
| single protein format | 1 | 1 | 8.5 |