Beta-lactamase TEM · SINGLE PROTEIN · Enterobacter cloacae
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As of 2026-09-14Protein identity stays anchored to UniProt Q6W9J1. Use UniProt Q6W9J1 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q6W9J1 as the stable identity anchor, then attach disease evidence before program review.
Beta-lactamase
Review this target as Beta-lactamase TEM, mapped to UniProt Q6W9J1. ChEMBL maps the protein component as Beta-lactamase. Sequence length is 286 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Beta-lactamase TEM as ChEMBL target CHEMBL3652, mapped to UniProt Q6W9J1. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Beta-lactamase TEM is the right protein anchor across sources, using UniProt Q6W9J1 as the stable mapping.
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| Preferred Name | Beta-lactamase TEM |
| Target Type | SINGLE PROTEIN |
| Organism | Enterobacter cloacae |
| UniProt | Q6W9J1 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Beta-lactamase |
| UniProt Accession | Q6W9J1 |
| Component Type | Protein |
| Sequence Length | 286 aa |
Beta-lactamase
Review this target as Beta-lactamase TEM, mapped to UniProt Q6W9J1. ChEMBL maps the protein component as Beta-lactamase. Sequence length is 286 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL433726 | 8.22 | IC50 | 6.0 | Preclinical |
| CHEMBL355558 | 7.85 | IC50 | 14.0 | Preclinical |
| CHEMBL169392 | 7.7 | IC50 | 20.0 | Preclinical |
| CHEMBL404 | 7.22 | IC50 | 60.0 | Approved |
| CHEMBL167539 | 7.16 | IC50 | 70.0 | Preclinical |
| CHEMBL353422 | 7.16 | IC50 | 70.0 | Preclinical |
| CHEMBL353613 | 7.05 | IC50 | 90.0 | Preclinical |
| CHEMBL355165 | 6.7 | IC50 | 200.0 | Preclinical |
| CHEMBL1439 | 6.5 | IC50 | 320.0 | Approved |
| CHEMBL353978 | 6.16 | IC50 | 700.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 8 | 30 | 5.9 |