Proto-oncogene tyrosine-protein kinase Src · SINGLE PROTEIN · Gallus gallus
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As of 2026-09-13Protein identity stays anchored to UniProt P00523. Use UniProt P00523 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P00523 as the stable identity anchor, then attach disease evidence before program review.
Proto-oncogene tyrosine-protein kinase Src
Review this target as Proto-oncogene tyrosine-protein kinase Src, mapped to UniProt P00523. Sequence length is 533 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Proto-oncogene tyrosine-protein kinase Src as ChEMBL target CHEMBL3655, mapped to UniProt P00523. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Proto-oncogene tyrosine-protein kinase Src |
| Target Type | SINGLE PROTEIN |
| Organism | Gallus gallus |
| UniProt | P00523 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Proto-oncogene tyrosine-protein kinase Src |
| UniProt Accession | P00523 |
| Component Type | Protein |
| Sequence Length | 533 aa |
Proto-oncogene tyrosine-protein kinase Src
Review this target as Proto-oncogene tyrosine-protein kinase Src, mapped to UniProt P00523. Sequence length is 533 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5209202 | 9.55 | Kd | 0.28 | Preclinical |
| CHEMBL5416410 | 9.4 | IC50 | 0.4 | Approved |
| CHEMBL1171837 | 9.05 | IC50 | 0.9 | Approved |
| CHEMBL285063 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL94061 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL91867 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL169390 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL598007 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL2403819 | 8.96 | IC50 | 1.1 | Preclinical |
| CHEMBL2403820 | 8.96 | IC50 | 1.1 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 27 | 197 | 6.8 |
| assay format | 15 | 35 | 6.9 |
| cell-based format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 2 | 21 | 6.0 |
| assay format | 1 | 16 | 6.2 |