Growth factor receptor-bound protein 2 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P62993. Use UniProt P62993 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P62993 as the stable identity anchor, then attach disease evidence before program review.
Growth factor receptor-bound protein 2
Review this target as Growth factor receptor-bound protein 2, mapped to UniProt P62993. Sequence length is 217 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Growth factor receptor-bound protein 2 as ChEMBL target CHEMBL3663, mapped to UniProt P62993. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Growth factor receptor-bound protein 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P62993 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Growth factor receptor-bound protein 2 |
| UniProt Accession | P62993 |
| Component Type | Protein |
| Sequence Length | 217 aa |
Growth factor receptor-bound protein 2
Review this target as Growth factor receptor-bound protein 2, mapped to UniProt P62993. Sequence length is 217 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL349373 | 10.12 | Kd | 0.075 | Preclinical |
| CHEMBL423988 | 10.12 | Kd | 0.075 | Preclinical |
| CHEMBL175456 | 10.01 | Kd | 0.097 | Preclinical |
| CHEMBL73003 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL72036 | 9.4 | IC50 | 0.4 | Preclinical |
| CHEMBL72694 | 9.05 | IC50 | 0.9 | Preclinical |
| CHEMBL3144403 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL77689 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL427641 | 8.96 | Kd | 1.1 | Preclinical |
| CHEMBL431982 | 8.92 | IC50 | 1.2 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 90 | 242 | 6.5 |
| cell-based format | 27 | 59 | 6.4 |
| assay format | 15 | 10 | 6.8 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 2 | 6.0 |
| tissue-based format | 1 | 0 | — |