5-hydroxytryptamine receptor 3A · SINGLE PROTEIN · Cavia porcellus
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As of 2026-09-13Protein identity stays anchored to UniProt O70212. Use UniProt O70212 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O70212 as the stable identity anchor, then attach disease evidence before program review.
5-hydroxytryptamine receptor 3A
Review this target as 5-hydroxytryptamine receptor 3A, mapped to UniProt O70212. Sequence length is 490 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats 5-hydroxytryptamine receptor 3A as ChEMBL target CHEMBL3666, mapped to UniProt O70212. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether 5-hydroxytryptamine receptor 3A is the right protein anchor across sources, using UniProt O70212 as the stable mapping.
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| Preferred Name | 5-hydroxytryptamine receptor 3A |
| Target Type | SINGLE PROTEIN |
| Organism | Cavia porcellus |
| UniProt | O70212 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | 5-hydroxytryptamine receptor 3A |
| UniProt Accession | O70212 |
| Component Type | Protein |
| Sequence Length | 490 aa |
5-hydroxytryptamine receptor 3A
Review this target as 5-hydroxytryptamine receptor 3A, mapped to UniProt O70212. Sequence length is 490 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL289469 | 8.4 | Ki | 3.981 | Approved |
| CHEMBL4228145 | 7.8 | Kd | 15.85 | Preclinical |
| CHEMBL4225725 | 7.7 | Kd | 19.95 | Preclinical |
| CHEMBL1668031 | 7.7 | Kd | 19.95 | Preclinical |
| CHEMBL1269981 | 7.6 | Kd | 25.12 | Preclinical |
| CHEMBL56564 | 7.52 | Kd | 30.2 | Clinical |
| CHEMBL1668032 | 7.5 | Kd | 31.62 | Preclinical |
| CHEMBL4225302 | 7.4 | Kd | 39.81 | Preclinical |
| CHEMBL184379 | 7.4 | Kd | 39.81 | Preclinical |
| CHEMBL4227570 | 7.3 | Kd | 50.12 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 17 | 21 | 6.3 |
| single protein format | 2 | 1 | 7.5 |
| assay format | 1 | 5 | 7.6 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 13 | 48 | 5.8 |