Skip to main content
Free research Free research Free target review with research home and workspace preview
Quick search ChEMBL 36
Loading Target Snapshot...
Querying ChEMBL database. This may take a few seconds.
Target Snapshot

CHEMBL3673 Target Snapshot

Beta-ketoacyl-[acyl-carrier-protein] synthase III · SINGLE PROTEIN · Staphylococcus aureus subsp. aureus Mu50

Back to Search Search this target Browse approvals Evidence Card
4Compounds
1Assays
0Approved Drugs
4.0Activities
Free Research Context

Research home keeps recent targets

This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.

Research home Demo workspace
Navigation

Switch target

Move to another high-traffic target or paste a specific ChEMBL target ID.

Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-15

Protein identity stays anchored to UniProt P68795. Use UniProt P68795 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt P68795 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-15
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Beta-ketoacyl-[acyl-carrier-protein] synthase III as ChEMBL target CHEMBL3673, mapped to UniProt P68795. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Beta-ketoacyl-[acyl-carrier-protein] synthase III
SINGLE PROTEIN · Staphylococcus aureus subsp. aureus Mu50
As of 2026-09-15
ChEMBL target ID
CHEMBL3673
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-15
www.ebi.ac.uk
UniProt accession
P68795
Beta-ketoacyl-[acyl-carrier-protein] synthase III
UniProt accession via ChEMBL component mapping As of 2026-09-15
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-15
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Beta-ketoacyl-[acyl-carrier-protein] synthase III is the right protein anchor across sources, using UniProt P68795 as the stable mapping.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

Jump to Disease Context
Need a meeting-ready explanation of why this target matters?
Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

Open Review-ready Card
Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameBeta-ketoacyl-[acyl-carrier-protein] synthase III
Target TypeSINGLE PROTEIN
OrganismStaphylococcus aureus subsp. aureus Mu50
UniProtP68795
ChEMBL ↗ UniProt ↗ NCBI Protein ↗

Next Actions

SearchRun a focused querySearch the database using this target name as the starting context. ApprovalsCheck approved moleculesSee which approved drugs connect back to this target and its surrounding signal space. FeedScan papers & updatesStay in the project thread while checking recent papers and platform updates.
UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelBeta-ketoacyl-[acyl-carrier-protein] synthase III
UniProt AccessionP68795
Component TypeProtein
Sequence Length313 aa

Beta-ketoacyl-[acyl-carrier-protein] synthase III

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as Beta-ketoacyl-[acyl-carrier-protein] synthase III, mapped to UniProt P68795. Sequence length is 313 aa.

Mapped IDP68795
Review nameBeta-ketoacyl-[acyl-carrier-protein] synthase III
OrganismStaphylococcus aureus subsp. aureus Mu50
Assay Mix

Activity Type Distribution

IC504.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL370931 5.42 IC50 3800.0 Preclinical
CHEMBL175848 5.0 IC50 10000.0 Preclinical
CHEMBL191827 4.91 IC50 12300.0 Preclinical
CHEMBL180466 4.62 IC50 24000.0 Preclinical
Distribution

pChEMBL Value Distribution

2
5.0
0
5.5
0
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

1
Total Assays
4
Tested Compounds
1
Assay Types
Binding — 1 assays, 4 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 1 4 5.0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine