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Target Snapshot

CHEMBL3706572 Target Snapshot

MOLM-13 · CELL-LINE · Homo sapiens

2,301Compounds
930Assays
15Approved Drugs
1,927.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats MOLM-13 as ChEMBL target CHEMBL3706572. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
MOLM-13
CELL-LINE · Homo sapiens
As of 2026-09-13
ChEMBL target ID
CHEMBL3706572
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether MOLM-13 still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

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Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelMOLM-13
UniProt AccessionN/A

MOLM-13

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as MOLM-13.

Review nameMOLM-13
OrganismHomo sapiens
Clinical Profile

Clinical Phase Distribution

15
Approved
9
Phase III
13
Phase II
7
Phase I
Assay Mix

Activity Type Distribution

IC501,725.0
EC50202.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL4790597 10.85 IC50 0.014 Preclinical
CHEMBL4557634 10.85 IC50 0.014 Preclinical
CHEMBL5405642 10.7 IC50 0.02 Preclinical
CHEMBL5085549 10.7 IC50 0.02 Preclinical
CHEMBL5077700 10.7 IC50 0.02 Preclinical
CHEMBL4439404 10.66 IC50 0.022 Preclinical
CHEMBL5083643 10.52 IC50 0.03 Preclinical
CHEMBL5437916 10.52 IC50 0.03 Preclinical
CHEMBL5075013 10.52 IC50 0.03 Preclinical
CHEMBL5073905 10.52 IC50 0.03 Preclinical
Distribution

pChEMBL Value Distribution

200
5.0
188
5.5
303
6.0
171
6.5
131
7.0
117
7.5
91
8.0
67
8.5
45
9.0
29
9.5
pChEMBL
Approved Drugs

Approved Drugs

QUIZARTINIB
CHEMBL576982
Approved 2023
PACRITINIB
CHEMBL2035187
Approved 2022
FEDRATINIB
CHEMBL1287853
Approved 2019
GILTERITINIB
CHEMBL3301622
Approved 2018
MIDOSTAURIN
CHEMBL608533
Approved 2017
VENETOCLAX
CHEMBL3137309
Approved 2016
PALBOCICLIB
CHEMBL189963
Approved 2015
SUNITINIB
CHEMBL535
Approved 2006
VORINOSTAT
CHEMBL98
Approved 2006
SORAFENIB
CHEMBL1336
Approved 2005
PACLITAXEL
CHEMBL428647
Approved 1992
COLCHICINE
CHEMBL107
Approved 1961
Assay Landscape

Assay Landscape

930
Total Assays
1,406
Tested Compounds
2
Assay Types
Functional — 925 assays, 1,406 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 818 1,406 6.5
organism-based format 106 0
assay format 1 0
ADME — 5 assays, 14 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 5 14 5.3

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine