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Target Snapshot

CHEMBL3707166 Target Snapshot

TOV112D · CELL-LINE · Homo sapiens

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53Compounds
16Assays
0Approved Drugs
76.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats TOV112D as ChEMBL target CHEMBL3707166. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
TOV112D
CELL-LINE · Homo sapiens
As of 2026-09-14
ChEMBL target ID
CHEMBL3707166
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

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Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether TOV112D still has a stable protein naming contract across sources.

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Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameTOV112D
Target TypeCELL-LINE
OrganismHomo sapiens
ChEMBL ↗

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelTOV112D
UniProt AccessionN/A

TOV112D

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as TOV112D.

Review nameTOV112D
OrganismHomo sapiens
Clinical Profile

Clinical Phase Distribution

1
Phase III
2
Phase II
Assay Mix

Activity Type Distribution

IC5047.0
EC5029.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL223250 9.0 EC50 1.0 Preclinical
CHEMBL4868447 8.4 EC50 4.0 Preclinical
CHEMBL1976486 8.3 EC50 5.0 Preclinical
CHEMBL386103 8.22 EC50 6.0 Preclinical
CHEMBL4871631 8.1 EC50 8.0 Preclinical
CHEMBL4866045 7.96 EC50 11.0 Preclinical
CHEMBL4863902 7.66 EC50 22.0 Preclinical
CHEMBL4869989 7.38 EC50 42.0 Preclinical
CHEMBL4864135 7.32 EC50 48.0 Preclinical
CHEMBL4867513 7.29 EC50 51.0 Preclinical
Distribution

pChEMBL Value Distribution

6
5.0
4
5.5
1
6.0
3
6.5
6
7.0
2
7.5
4
8.0
0
8.5
1
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

16
Total Assays
37
Tested Compounds
1
Assay Types
Functional — 16 assays, 37 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 14 37 5.3
organism-based format 2 0 —

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine