Use UniProt Q13427 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL3707467 Target Snapshot
Peptidyl-prolyl cis-trans isomerase G · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q13427. Use UniProt Q13427 as the stable identity anchor, then attach disease evidence before program review.
Peptidyl-prolyl cis-trans isomerase G
Review this target as Peptidyl-prolyl cis-trans isomerase G, mapped to UniProt Q13427. Sequence length is 754 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Peptidyl-prolyl cis-trans isomerase G as ChEMBL target CHEMBL3707467, mapped to UniProt Q13427. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Peptidyl-prolyl cis-trans isomerase G is the right protein anchor across sources, using UniProt Q13427 as the stable mapping.
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| Preferred Name | Peptidyl-prolyl cis-trans isomerase G |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q13427 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Peptidyl-prolyl cis-trans isomerase G |
| UniProt Accession | Q13427 |
| Component Type | Protein |
| Sequence Length | 754 aa |
Peptidyl-prolyl cis-trans isomerase G
How to read this target
Review this target as Peptidyl-prolyl cis-trans isomerase G, mapped to UniProt Q13427. Sequence length is 754 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1232461 | 8.0 | IC50 | 10.0 | Clinical |
| CHEMBL1232461 | 7.96 | Kd | 11.0 | Clinical |
| CHEMBL3647433 | 6.43 | IC50 | 370.0 | Preclinical |
| CHEMBL3647432 | 6.25 | IC50 | 560.0 | Preclinical |
| CHEMBL3647436 | 6.1 | IC50 | 790.0 | Preclinical |
| CHEMBL3647431 | 5.82 | IC50 | 1500.0 | Preclinical |
| CHEMBL3647430 | 5.55 | IC50 | 2800.0 | Preclinical |
| CHEMBL3647435 | 5.51 | IC50 | 3100.0 | Preclinical |
| CHEMBL3647434 | 5.48 | IC50 | 3300.0 | Preclinical |
| CHEMBL3639462 | 5.47 | IC50 | 3400.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 8 assays, 11 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 8 | 11 | 6.0 |