Skip to main content
Free research Free research Free target review with research home and workspace preview
Quick search ChEMBL 36
Loading Target Snapshot...
Querying ChEMBL database. This may take a few seconds.
Target Snapshot

CHEMBL3707467 Target Snapshot

Peptidyl-prolyl cis-trans isomerase G · SINGLE PROTEIN · Homo sapiens

11Compounds
8Assays
0Approved Drugs
12.0Activities
Free Research Context

Research home keeps recent targets

This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.

Navigation

Switch target

Move to another high-traffic target or paste a specific ChEMBL target ID.

Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt Q13427. Use UniProt Q13427 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q13427 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Peptidyl-prolyl cis-trans isomerase G as ChEMBL target CHEMBL3707467, mapped to UniProt Q13427. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Peptidyl-prolyl cis-trans isomerase G
SINGLE PROTEIN · Homo sapiens
As of 2026-09-14
ChEMBL target ID
CHEMBL3707467
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
Q13427
Peptidyl-prolyl cis-trans isomerase G
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Peptidyl-prolyl cis-trans isomerase G is the right protein anchor across sources, using UniProt Q13427 as the stable mapping.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

Jump to Disease Context
Need a meeting-ready explanation of why this target matters?
Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

Open Review-ready Card
Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelPeptidyl-prolyl cis-trans isomerase G
UniProt AccessionQ13427
Component TypeProtein
Sequence Length754 aa

Peptidyl-prolyl cis-trans isomerase G

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Peptidyl-prolyl cis-trans isomerase G, mapped to UniProt Q13427. Sequence length is 754 aa.

Mapped IDQ13427
Review namePeptidyl-prolyl cis-trans isomerase G
OrganismHomo sapiens
Clinical Profile

Clinical Phase Distribution

2
Phase II
Assay Mix

Activity Type Distribution

IC5011.0
KD1.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL1232461 8.0 IC50 10.0 Clinical
CHEMBL1232461 7.96 Kd 11.0 Clinical
CHEMBL3647433 6.43 IC50 370.0 Preclinical
CHEMBL3647432 6.25 IC50 560.0 Preclinical
CHEMBL3647436 6.1 IC50 790.0 Preclinical
CHEMBL3647431 5.82 IC50 1500.0 Preclinical
CHEMBL3647430 5.55 IC50 2800.0 Preclinical
CHEMBL3647435 5.51 IC50 3100.0 Preclinical
CHEMBL3647434 5.48 IC50 3300.0 Preclinical
CHEMBL3639462 5.47 IC50 3400.0 Preclinical
Distribution

pChEMBL Value Distribution

3
5.0
3
5.5
3
6.0
0
6.5
0
7.0
1
7.5
1
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

8
Total Assays
11
Tested Compounds
1
Assay Types
Binding — 8 assays, 11 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 8 11 6.0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine