Beta-adrenergic receptor kinase 1 · SINGLE PROTEIN · Bos taurus
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As of 2026-09-13Protein identity stays anchored to UniProt P21146. Use UniProt P21146 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P21146 as the stable identity anchor, then attach disease evidence before program review.
Beta-adrenergic receptor kinase 1
Review this target as Beta-adrenergic receptor kinase 1, mapped to UniProt P21146. Sequence length is 689 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Beta-adrenergic receptor kinase 1 as ChEMBL target CHEMBL3711550, mapped to UniProt P21146. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Beta-adrenergic receptor kinase 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Bos taurus |
| UniProt | P21146 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Beta-adrenergic receptor kinase 1 |
| UniProt Accession | P21146 |
| Component Type | Protein |
| Sequence Length | 689 aa |
Beta-adrenergic receptor kinase 1
Review this target as Beta-adrenergic receptor kinase 1, mapped to UniProt P21146. Sequence length is 689 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1738878 | 7.7 | IC50 | 20.0 | Preclinical |
| CHEMBL1738877 | 7.52 | IC50 | 30.0 | Preclinical |
| CHEMBL4090144 | 7.52 | IC50 | 30.0 | Preclinical |
| CHEMBL4097393 | 7.52 | IC50 | 30.0 | Preclinical |
| CHEMBL60254 | 7.46 | IC50 | 35.0 | Preclinical |
| CHEMBL5712043 | 7.46 | IC50 | 35.0 | Preclinical |
| CHEMBL3809020 | 6.89 | IC50 | 130.0 | Preclinical |
| CHEMBL384073 | 6.6 | IC50 | 250.0 | Preclinical |
| CHEMBL4087244 | 6.41 | IC50 | 390.0 | Preclinical |
| CHEMBL3950887 | 6.22 | IC50 | 600.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 6 | 74 | 5.6 |
| cell-based format | 2 | 13 | 4.9 |
| single protein format | 2 | 7 | 5.8 |