Skip to main content
Free research Free research Free target review with research home and workspace preview
Quick search ChEMBL 36
Loading Target Snapshot...
Querying ChEMBL database. This may take a few seconds.
Target Snapshot

CHEMBL3713687 Target Snapshot

Cytochrome P450 26B1 · SINGLE PROTEIN · Homo sapiens

56Compounds
6Assays
2Approved Drugs
77.0Activities
Free Research Context

Research home keeps recent targets

This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.

Navigation

Switch target

Move to another high-traffic target or paste a specific ChEMBL target ID.

Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt Q9NR63. Use UniProt Q9NR63 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q9NR63 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Cytochrome P450 26B1 as ChEMBL target CHEMBL3713687, mapped to UniProt Q9NR63. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Cytochrome P450 26B1
SINGLE PROTEIN · Homo sapiens
As of 2026-09-14
ChEMBL target ID
CHEMBL3713687
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
Q9NR63
Cytochrome P450 26B1
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Cytochrome P450 26B1 is the right protein anchor across sources, using UniProt Q9NR63 as the stable mapping.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

Jump to Disease Context
Need a meeting-ready explanation of why this target matters?
Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

Open Review-ready Card
Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelCytochrome P450 26B1
UniProt AccessionQ9NR63
Component TypeProtein
Sequence Length512 aa

Cytochrome P450 26B1

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Cytochrome P450 26B1, mapped to UniProt Q9NR63. Sequence length is 512 aa.

Mapped IDQ9NR63
Review nameCytochrome P450 26B1
OrganismHomo sapiens
Clinical Profile

Clinical Phase Distribution

2
Approved
2
Phase II
Assay Mix

Activity Type Distribution

IC5077.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL459505 9.34 IC50 0.46 Clinical
CHEMBL5785788 8.51 IC50 3.1 Preclinical
CHEMBL389433 7.75 IC50 18.0 Clinical
CHEMBL157101 6.85 IC50 140.0 Approved
CHEMBL5934332 6.7 IC50 200.0 Preclinical
CHEMBL5961796 6.54 IC50 290.0 Preclinical
CHEMBL5972108 6.3 IC50 500.0 Preclinical
CHEMBL309282 6.28 IC50 520.0 Preclinical
CHEMBL5850367 6.26 IC50 550.0 Preclinical
CHEMBL3787323 6.17 IC50 680.0 Preclinical
Distribution

pChEMBL Value Distribution

8
5.0
9
5.5
6
6.0
4
6.5
0
7.0
2
7.5
0
8.0
1
8.5
2
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

KETOCONAZOLE
CHEMBL157101
Approved 1981
Assay Landscape

Assay Landscape

6
Total Assays
41
Tested Compounds
1
Assay Types
Binding — 6 assays, 41 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 4 29 5.4
single protein format 2 12 6.2

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine