Sodium- and chloride-dependent betaine transporter · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P48065. Use UniProt P48065 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P48065 as the stable identity anchor, then attach disease evidence before program review.
Sodium- and chloride-dependent betaine transporter
Review this target as Sodium- and chloride-dependent betaine transporter, mapped to UniProt P48065. Sequence length is 614 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Sodium- and chloride-dependent betaine transporter as ChEMBL target CHEMBL3715, mapped to UniProt P48065. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Sodium- and chloride-dependent betaine transporter |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P48065 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Sodium- and chloride-dependent betaine transporter |
| UniProt Accession | P48065 |
| Component Type | Protein |
| Sequence Length | 614 aa |
Sodium- and chloride-dependent betaine transporter
Review this target as Sodium- and chloride-dependent betaine transporter, mapped to UniProt P48065. Sequence length is 614 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3326391 | 6.23 | IC50 | 590.0 | Preclinical |
| CHEMBL96 | 6.07 | IC50 | 851.14 | Preclinical |
| CHEMBL1164505 | 5.8 | Ki | 1600.0 | Preclinical |
| CHEMBL1882801 | 5.79 | IC50 | 1621.81 | Preclinical |
| CHEMBL4526098 | 5.52 | IC50 | 3000.0 | Preclinical |
| CHEMBL349005 | 5.4 | IC50 | 3981.07 | Preclinical |
| CHEMBL1446457 | 5.29 | IC50 | 5100.0 | Preclinical |
| CHEMBL2415009 | 5.26 | IC50 | 5480.0 | Preclinical |
| CHEMBL3040189 | 5.26 | IC50 | 5480.0 | Preclinical |
| CHEMBL4458674 | 5.14 | IC50 | 7300.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 39 | 23 | 5.0 |
| single protein format | 9 | 23 | 4.7 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 5 | — |
| cell-based format | 1 | 1 | 4.4 |