5-hydroxytryptamine receptor 1A · SINGLE PROTEIN · Mus musculus
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As of 2026-09-13Protein identity stays anchored to UniProt Q64264. Use UniProt Q64264 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q64264 as the stable identity anchor, then attach disease evidence before program review.
5-hydroxytryptamine receptor 1A
Review this target as 5-hydroxytryptamine receptor 1A, mapped to UniProt Q64264. Sequence length is 421 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats 5-hydroxytryptamine receptor 1A as ChEMBL target CHEMBL3737, mapped to UniProt Q64264. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | 5-hydroxytryptamine receptor 1A |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | Q64264 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | 5-hydroxytryptamine receptor 1A |
| UniProt Accession | Q64264 |
| Component Type | Protein |
| Sequence Length | 421 aa |
5-hydroxytryptamine receptor 1A
Review this target as 5-hydroxytryptamine receptor 1A, mapped to UniProt Q64264. Sequence length is 421 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL10270 | 9.7 | Ki | 0.2 | Preclinical |
| CHEMBL63449 | 9.7 | Ki | 0.2 | Preclinical |
| CHEMBL65274 | 9.7 | Ki | 0.2 | Preclinical |
| CHEMBL26118 | 9.4 | Ki | 0.4 | Preclinical |
| CHEMBL26998 | 9.3 | Ki | 0.5 | Preclinical |
| CHEMBL3946661 | 9.22 | Ki | 0.6 | Preclinical |
| CHEMBL28437 | 9.1 | Ki | 0.8 | Preclinical |
| CHEMBL141438 | 8.89 | IC50 | 1.3 | Preclinical |
| CHEMBL2021539 | 8.89 | Ki | 1.3 | Preclinical |
| CHEMBL356743 | 8.72 | IC50 | 1.9 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 23 | 41 | 7.7 |
| tissue-based format | 6 | 6 | 4.8 |
| cell-based format | 4 | 7 | 7.8 |
| organism-based format | 2 | 4 | 7.9 |
| assay format | 1 | 19 | 6.0 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| organism-based format | 9 | 0 | — |
| assay format | 5 | 0 | — |