Use UniProt A0A0C5PRQ1 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL3739251 Target Snapshot
Zinc metalloproteinase dpy-31 · SINGLE PROTEIN · Teladorsagia circumcincta
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As of 2026-09-15Protein identity stays anchored to UniProt A0A0C5PRQ1. Use UniProt A0A0C5PRQ1 as the stable identity anchor, then attach disease evidence before program review.
Zinc metalloproteinase dpy-31
Review this target as Zinc metalloproteinase dpy-31, mapped to UniProt A0A0C5PRQ1. Sequence length is 614 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Zinc metalloproteinase dpy-31 as ChEMBL target CHEMBL3739251, mapped to UniProt A0A0C5PRQ1. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Zinc metalloproteinase dpy-31 |
| Target Type | SINGLE PROTEIN |
| Organism | Teladorsagia circumcincta |
| UniProt | A0A0C5PRQ1 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Zinc metalloproteinase dpy-31 |
| UniProt Accession | A0A0C5PRQ1 |
| Component Type | Protein |
| Sequence Length | 614 aa |
Zinc metalloproteinase dpy-31
How to read this target
Review this target as Zinc metalloproteinase dpy-31, mapped to UniProt A0A0C5PRQ1. Sequence length is 614 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3740110 | 4.6 | IC50 | 25118.86 | Preclinical |
| CHEMBL3740431 | 4.5 | IC50 | 31622.78 | Preclinical |
| CHEMBL226853 | 4.4 | IC50 | 39810.72 | Preclinical |
| CHEMBL279785 | 4.1 | IC50 | 79432.82 | Clinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 1 assays, 4 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 4 | 4.4 |