Beta-glucosidase · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q9HCG7. Use UniProt Q9HCG7 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9HCG7 as the stable identity anchor, then attach disease evidence before program review.
Non-lysosomal glucosylceramidase
Review this target as Beta-glucosidase, mapped to UniProt Q9HCG7. ChEMBL maps the protein component as Non-lysosomal glucosylceramidase. Sequence length is 927 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Beta-glucosidase as ChEMBL target CHEMBL3761, mapped to UniProt Q9HCG7. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Beta-glucosidase is the right protein anchor across sources, using UniProt Q9HCG7 as the stable mapping.
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| Preferred Name | Beta-glucosidase |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9HCG7 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Non-lysosomal glucosylceramidase |
| UniProt Accession | Q9HCG7 |
| Component Type | Protein |
| Sequence Length | 927 aa |
Non-lysosomal glucosylceramidase
Review this target as Beta-glucosidase, mapped to UniProt Q9HCG7. ChEMBL maps the protein component as Non-lysosomal glucosylceramidase. Sequence length is 927 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3354624 | 10.1 | IC50 | 0.08 | Preclinical |
| CHEMBL3354625 | 10.1 | IC50 | 0.08 | Preclinical |
| CHEMBL3354627 | 10.1 | IC50 | 0.08 | Preclinical |
| CHEMBL3354634 | 10.0 | IC50 | 0.1 | Preclinical |
| CHEMBL3354635 | 10.0 | IC50 | 0.1 | Preclinical |
| CHEMBL3354626 | 9.92 | IC50 | 0.12 | Preclinical |
| CHEMBL574645 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL1651630 | 9.4 | IC50 | 0.4 | Preclinical |
| CHEMBL3354636 | 9.4 | IC50 | 0.4 | Preclinical |
| CHEMBL3354041 | 9.3 | IC50 | 0.5 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 25 | 131 | 7.5 |
| assay format | 6 | 6 | 6.9 |
| cell-based format | 5 | 17 | 7.5 |