Serine protease 1 · SINGLE PROTEIN · Bos taurus
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As of 2026-09-14Protein identity stays anchored to UniProt P00760. Use UniProt P00760 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P00760 as the stable identity anchor, then attach disease evidence before program review.
Serine protease 1
Review this target as Serine protease 1, mapped to UniProt P00760. Sequence length is 246 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Serine protease 1 as ChEMBL target CHEMBL3769, mapped to UniProt P00760. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Serine protease 1 is the right protein anchor across sources, using UniProt P00760 as the stable mapping.
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| Preferred Name | Serine protease 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Bos taurus |
| UniProt | P00760 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Serine protease 1 |
| UniProt Accession | P00760 |
| Component Type | Protein |
| Sequence Length | 246 aa |
Serine protease 1
Review this target as Serine protease 1, mapped to UniProt P00760. Sequence length is 246 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1801042 | 10.7 | Ki | 0.02 | Preclinical |
| CHEMBL4210529 | 10.7 | Ki | 0.02 | Preclinical |
| CHEMBL4211294 | 10.7 | Ki | 0.02 | Preclinical |
| CHEMBL4212172 | 10.7 | Ki | 0.02 | Preclinical |
| CHEMBL4217569 | 10.7 | Ki | 0.02 | Preclinical |
| CHEMBL4217607 | 10.7 | Ki | 0.02 | Preclinical |
| CHEMBL28817 | 10.57 | Ki | 0.027 | Preclinical |
| CHEMBL273196 | 10.35 | IC50 | 0.045 | Clinical |
| CHEMBL4164510 | 10.34 | Ki | 0.046 | Preclinical |
| CHEMBL36744 | 10.27 | Ki | 0.054 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 165 | 791 | 6.5 |
| assay format | 1 | 1 | 7.8 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 9 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 0 | — |