Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A · SINGLE PROTEIN · Bos taurus
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As of 2026-09-14Protein identity stays anchored to UniProt P14100. Use UniProt P14100 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P14100 as the stable identity anchor, then attach disease evidence before program review.
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A
Review this target as Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A, mapped to UniProt P14100. Sequence length is 530 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A as ChEMBL target CHEMBL3774, mapped to UniProt P14100. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A |
| Target Type | SINGLE PROTEIN |
| Organism | Bos taurus |
| UniProt | P14100 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A |
| UniProt Accession | P14100 |
| Component Type | Protein |
| Sequence Length | 530 aa |
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A
Review this target as Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A, mapped to UniProt P14100. Sequence length is 530 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL278254 | 8.22 | IC50 | 6.0 | Preclinical |
| CHEMBL18524 | 7.92 | IC50 | 12.0 | Preclinical |
| CHEMBL18744 | 7.85 | IC50 | 14.0 | Preclinical |
| CHEMBL18965 | 7.85 | IC50 | 14.0 | Preclinical |
| CHEMBL19157 | 7.82 | IC50 | 15.0 | Preclinical |
| CHEMBL274965 | 7.6 | IC50 | 25.0 | Preclinical |
| CHEMBL416541 | 7.6 | IC50 | 25.0 | Preclinical |
| CHEMBL19046 | 7.51 | IC50 | 31.0 | Preclinical |
| CHEMBL18817 | 7.48 | IC50 | 33.0 | Preclinical |
| CHEMBL18745 | 7.44 | IC50 | 36.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 3 | 21 | 6.8 |