Small conductance calcium-activated potassium channel protein 3 · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt P70605. Use UniProt P70605 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P70605 as the stable identity anchor, then attach disease evidence before program review.
Small conductance calcium-activated potassium channel protein 3
Review this target as Small conductance calcium-activated potassium channel protein 3, mapped to UniProt P70605. Sequence length is 732 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Small conductance calcium-activated potassium channel protein 3 as ChEMBL target CHEMBL3780, mapped to UniProt P70605. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Small conductance calcium-activated potassium channel protein 3 is the right protein anchor across sources, using UniProt P70605 as the stable mapping.
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| Preferred Name | Small conductance calcium-activated potassium channel protein 3 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P70605 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Small conductance calcium-activated potassium channel protein 3 |
| UniProt Accession | P70605 |
| Component Type | Protein |
| Sequence Length | 732 aa |
Small conductance calcium-activated potassium channel protein 3
Review this target as Small conductance calcium-activated potassium channel protein 3, mapped to UniProt P70605. Sequence length is 732 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL420873 | 9.37 | Kd | 0.43 | Preclinical |
| CHEMBL420873 | 8.85 | Ki | 1.4 | Preclinical |
| CHEMBL2391662 | 8.77 | IC50 | 1.7 | Preclinical |
| CHEMBL117908 | 8.74 | Ki | 1.8 | Preclinical |
| CHEMBL2391665 | 8.64 | IC50 | 2.3 | Preclinical |
| CHEMBL2391673 | 8.59 | IC50 | 2.6 | Preclinical |
| CHEMBL117908 | 8.57 | Kd | 2.7 | Preclinical |
| CHEMBL185463 | 8.57 | IC50 | 2.7 | Preclinical |
| CHEMBL2391668 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL2391675 | 8.52 | IC50 | 3.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 8 | 49 | 6.5 |
| single protein format | 4 | 57 | 7.8 |