Fatty acid synthase · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt P12785. Use UniProt P12785 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P12785 as the stable identity anchor, then attach disease evidence before program review.
Fatty acid synthase
Review this target as Fatty acid synthase, mapped to UniProt P12785. Sequence length is 2505 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Fatty acid synthase as ChEMBL target CHEMBL3783, mapped to UniProt P12785. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Fatty acid synthase is the right protein anchor across sources, using UniProt P12785 as the stable mapping.
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| Preferred Name | Fatty acid synthase |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P12785 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Fatty acid synthase |
| UniProt Accession | P12785 |
| Component Type | Protein |
| Sequence Length | 2505 aa |
Fatty acid synthase
Review this target as Fatty acid synthase, mapped to UniProt P12785. Sequence length is 2505 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL212547 | 7.3 | IC50 | 50.0 | Preclinical |
| CHEMBL2322360 | 7.21 | IC50 | 62.0 | Preclinical |
| CHEMBL380035 | 7.14 | IC50 | 73.0 | Preclinical |
| CHEMBL378610 | 7.07 | IC50 | 86.0 | Preclinical |
| CHEMBL379396 | 6.91 | IC50 | 122.0 | Preclinical |
| CHEMBL214763 | 6.87 | IC50 | 134.0 | Preclinical |
| CHEMBL211838 | 6.76 | IC50 | 173.0 | Preclinical |
| CHEMBL214764 | 6.76 | IC50 | 172.0 | Preclinical |
| CHEMBL2322359 | 6.5 | IC50 | 316.0 | Preclinical |
| CHEMBL2322370 | 6.5 | IC50 | 316.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 6 | 24 | 5.0 |
| organism-based format | 4 | 0 | — |
| single protein format | 2 | 30 | 6.1 |
| cell-based format | 1 | 1 | 7.2 |