Lysine-specific demethylase 3B · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q7LBC6. Use UniProt Q7LBC6 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q7LBC6 as the stable identity anchor, then attach disease evidence before program review.
Lysine-specific demethylase 3B
Review this target as Lysine-specific demethylase 3B, mapped to UniProt Q7LBC6. Sequence length is 1761 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Lysine-specific demethylase 3B as ChEMBL target CHEMBL3784906, mapped to UniProt Q7LBC6. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Lysine-specific demethylase 3B |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q7LBC6 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Lysine-specific demethylase 3B |
| UniProt Accession | Q7LBC6 |
| Component Type | Protein |
| Sequence Length | 1761 aa |
Lysine-specific demethylase 3B
Review this target as Lysine-specific demethylase 3B, mapped to UniProt Q7LBC6. Sequence length is 1761 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5193187 | 6.89 | Kd | 130.0 | Preclinical |
| CHEMBL3183531 | 5.16 | IC50 | 6900.0 | Preclinical |
| CHEMBL5173150 | 5.11 | Kd | 7790.0 | Preclinical |
| CHEMBL5191875 | 4.79 | Kd | 16300.0 | Preclinical |
| CHEMBL5071515 | 4.57 | IC50 | 26700.0 | Preclinical |
| CHEMBL5072902 | 4.32 | IC50 | 47600.0 | Preclinical |
| CHEMBL5071002 | 4.29 | IC50 | 51200.0 | Preclinical |
| CHEMBL5080728 | 4.27 | IC50 | 53200.0 | Preclinical |
| CHEMBL5084638 | 4.27 | IC50 | 54200.0 | Preclinical |
| CHEMBL5081435 | 4.25 | IC50 | 56200.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 9 | 1 | 5.2 |
| cell-based format | 4 | 15 | 4.5 |