Use UniProt Q15652 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL3792271 Target Snapshot
Probable JmjC domain-containing histone demethylation protein 2C · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q15652. Use UniProt Q15652 as the stable identity anchor, then attach disease evidence before program review.
Probable JmjC domain-containing histone demethylation protein 2C
Review this target as Probable JmjC domain-containing histone demethylation protein 2C, mapped to UniProt Q15652. Sequence length is 2540 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Probable JmjC domain-containing histone demethylation protein 2C as ChEMBL target CHEMBL3792271, mapped to UniProt Q15652. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Probable JmjC domain-containing histone demethylation protein 2C is the right protein anchor across sources, using UniProt Q15652 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Probable JmjC domain-containing histone demethylation protein 2C |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q15652 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Probable JmjC domain-containing histone demethylation protein 2C |
| UniProt Accession | Q15652 |
| Component Type | Protein |
| Sequence Length | 2540 aa |
Probable JmjC domain-containing histone demethylation protein 2C
How to read this target
Review this target as Probable JmjC domain-containing histone demethylation protein 2C, mapped to UniProt Q15652. Sequence length is 2540 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3793278 | 5.72 | IC50 | 1900.0 | Preclinical |
| CHEMBL5193187 | 5.57 | Kd | 2700.0 | Preclinical |
| CHEMBL5173150 | 5.09 | Kd | 8060.0 | Preclinical |
| CHEMBL5191875 | 4.57 | Kd | 26700.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 2 assays, 4 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 3 | 5.1 |
| single protein format | 1 | 1 | 5.7 |