Neuromedin-K receptor · SINGLE PROTEIN · Cavia porcellus
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As of 2026-09-13Protein identity stays anchored to UniProt P30098. Use UniProt P30098 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P30098 as the stable identity anchor, then attach disease evidence before program review.
Neuromedin-K receptor
Review this target as Neuromedin-K receptor, mapped to UniProt P30098. Sequence length is 440 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Neuromedin-K receptor as ChEMBL target CHEMBL3799, mapped to UniProt P30098. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Neuromedin-K receptor is the right protein anchor across sources, using UniProt P30098 as the stable mapping.
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| Preferred Name | Neuromedin-K receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Cavia porcellus |
| UniProt | P30098 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Neuromedin-K receptor |
| UniProt Accession | P30098 |
| Component Type | Protein |
| Sequence Length | 440 aa |
Neuromedin-K receptor
Review this target as Neuromedin-K receptor, mapped to UniProt P30098. Sequence length is 440 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL346178 | 10.1 | Kd | 0.08 | Clinical |
| CHEMBL583102 | 9.22 | EC50 | 0.6 | Preclinical |
| CHEMBL346178 | 9.22 | Ki | 0.6 | Clinical |
| CHEMBL2115415 | 9.14 | IC50 | 0.72 | Preclinical |
| CHEMBL81919 | 9.05 | EC50 | 0.9 | Preclinical |
| CHEMBL565894 | 8.8 | Ki | 1.6 | Preclinical |
| CHEMBL437797 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL295615 | 8.57 | IC50 | 2.7 | Preclinical |
| CHEMBL567849 | 8.57 | Ki | 2.7 | Preclinical |
| CHEMBL45340 | 8.43 | IC50 | 3.7 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 10 | 19 | 6.3 |
| cell membrane format | 8 | 11 | 7.6 |
| cell-based format | 6 | 5 | 8.8 |
| single protein format | 2 | 0 | — |
| assay format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 4 | 3 | 8.4 |
| cell-based format | 3 | 6 | 8.1 |
| assay format | 1 | 0 | — |