Gamma-butyrobetaine dioxygenase · SINGLE PROTEIN · Pseudomonas sp. (strain AK-1)
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As of 2026-09-14Protein identity stays anchored to UniProt P80193. Use UniProt P80193 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P80193 as the stable identity anchor, then attach disease evidence before program review.
Gamma-butyrobetaine dioxygenase
Review this target as Gamma-butyrobetaine dioxygenase, mapped to UniProt P80193. Sequence length is 383 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Gamma-butyrobetaine dioxygenase as ChEMBL target CHEMBL3817724, mapped to UniProt P80193. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Gamma-butyrobetaine dioxygenase is the right protein anchor across sources, using UniProt P80193 as the stable mapping.
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| Preferred Name | Gamma-butyrobetaine dioxygenase |
| Target Type | SINGLE PROTEIN |
| Organism | Pseudomonas sp. (strain AK-1) |
| UniProt | P80193 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Gamma-butyrobetaine dioxygenase |
| UniProt Accession | P80193 |
| Component Type | Protein |
| Sequence Length | 383 aa |
Gamma-butyrobetaine dioxygenase
Review this target as Gamma-butyrobetaine dioxygenase, mapped to UniProt P80193. Sequence length is 383 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL485023 | 6.7 | IC50 | 200.0 | Preclinical |
| CHEMBL426560 | 6.68 | IC50 | 210.0 | Preclinical |
| CHEMBL485022 | 6.66 | IC50 | 220.0 | Preclinical |
| CHEMBL2419266 | 6.05 | IC50 | 900.0 | Preclinical |
| CHEMBL2338328 | 6.0 | IC50 | 1000.0 | Preclinical |
| CHEMBL485022 | 4.82 | Kd | 15000.0 | Preclinical |
| CHEMBL2419267 | 4.75 | IC50 | 18000.0 | Preclinical |
| CHEMBL485023 | 4.7 | Kd | 20000.0 | Preclinical |
| CHEMBL2419272 | 4.66 | IC50 | 22000.0 | Preclinical |
| CHEMBL426560 | 4.66 | Kd | 22000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 6 | 15 | 4.9 |