AP2-associated protein kinase 1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q2M2I8. Use UniProt Q2M2I8 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q2M2I8 as the stable identity anchor, then attach disease evidence before program review.
AP2-associated protein kinase 1
Review this target as AP2-associated protein kinase 1, mapped to UniProt Q2M2I8. Sequence length is 961 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats AP2-associated protein kinase 1 as ChEMBL target CHEMBL3830, mapped to UniProt Q2M2I8. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | AP2-associated protein kinase 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q2M2I8 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | AP2-associated protein kinase 1 |
| UniProt Accession | Q2M2I8 |
| Component Type | Protein |
| Sequence Length | 961 aa |
AP2-associated protein kinase 1
Review this target as AP2-associated protein kinase 1, mapped to UniProt Q2M2I8. Sequence length is 961 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4085072 | 10.15 | IC50 | 0.07 | Preclinical |
| CHEMBL5742959 | 10.15 | IC50 | 0.07 | Preclinical |
| CHEMBL5178245 | 9.72 | IC50 | 0.19 | Preclinical |
| CHEMBL4544854 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL5186783 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL5202896 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL5783442 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL4065155 | 9.64 | IC50 | 0.23 | Preclinical |
| CHEMBL5928143 | 9.62 | IC50 | 0.24 | Preclinical |
| CHEMBL5842118 | 9.6 | IC50 | 0.25 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 147 | 873 | 8.0 |
| assay format | 33 | 66 | 7.4 |
| cell-based format | 21 | 133 | 7.6 |
| subcellular format | 6 | 51 | 6.6 |