Cardiac myosin · PROTEIN COMPLEX · Homo sapiens
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As of 2026-09-13Cardiac myosin shows approved-linked disease relevance led by cardiovascular disease. 3 more disease programs remain visible in the same review block. 2 linked drugs keep the current disease frame grounded. Protein identity stays anchored to UniProt P12883. Start with cardiovascular disease, then reuse UniProt P12883 as the stable protein anchor across project notes and exports.
Start with cardiovascular disease, then reuse UniProt P12883 as the stable protein anchor across project notes and exports.
Cardiac myosin shows approved-linked disease relevance led by cardiovascular disease. 3 more disease programs remain visible in the same review block. 2 linked drugs remain visible in the same block.
Start review with cardiovascular disease because it currently carries approved-linked support. Linked drugs include MAVACAMTEN, OMECAMTIV MECARBIL. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.
Disease source · ChEMBL drug mechanism + indication proxyMyosin-7
Review this target as Cardiac myosin, mapped to UniProt P12883. ChEMBL maps the protein component as Myosin-7. Sequence length is 1935 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Cardiac myosin as ChEMBL target CHEMBL3831286, mapped to UniProt P12883. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether Cardiac myosin is the right protein anchor across sources, using UniProt P12883 as the stable mapping.
Jump to Protein ContextUse this block first when you need to confirm why cardiovascular disease is currently framed as approved-linked support. It currently carries 2 linked drugs in the same disease frame.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardVerify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | Cardiac myosin |
| Target Type | PROTEIN COMPLEX |
| Organism | Homo sapiens |
| UniProt | P12883 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Myosin-7 |
| UniProt Accession | P12883 |
| Component Type | Protein |
| Sequence Length | 1935 aa |
Myosin-7
Review this target as Cardiac myosin, mapped to UniProt P12883. ChEMBL maps the protein component as Myosin-7. Sequence length is 1935 aa.
Open Targets-ready disease context using the current target-indication evidence contract.
Cardiac myosin shows approved-linked disease relevance led by cardiovascular disease. 3 more disease programs remain visible in the same review block.
Start review with cardiovascular disease because it currently carries approved-linked support. Linked drugs include MAVACAMTEN, OMECAMTIV MECARBIL. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.