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Target Snapshot

CHEMBL3831325 Target Snapshot

Uncharacterized protein · SINGLE PROTEIN · Pan troglodytes

40Compounds
1Assays
0Approved Drugs
40.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt A0A2J8P2M1. Use UniProt A0A2J8P2M1 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt A0A2J8P2M1 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Uncharacterized protein as ChEMBL target CHEMBL3831325, mapped to UniProt A0A2J8P2M1. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Uncharacterized protein
SINGLE PROTEIN · Pan troglodytes
As of 2026-09-14
ChEMBL target ID
CHEMBL3831325
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
A0A2J8P2M1
Purinergic receptor P2Y14
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Uncharacterized protein is the right protein anchor across sources, using UniProt A0A2J8P2M1 as the stable mapping.

Jump to Protein Context
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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

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Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelPurinergic receptor P2Y14
UniProt AccessionA0A2J8P2M1
Component TypeProtein
Sequence Length338 aa

Purinergic receptor P2Y14

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Uncharacterized protein, mapped to UniProt A0A2J8P2M1. ChEMBL maps the protein component as Purinergic receptor P2Y14. Sequence length is 338 aa.

Mapped IDA0A2J8P2M1
Review nameUncharacterized protein
OrganismPan troglodytes
Assay Mix

Activity Type Distribution

IC5040.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL1800685 8.66 IC50 2.2 Preclinical
CHEMBL3716776 8.52 IC50 3.0 Preclinical
CHEMBL1774903 8.27 IC50 5.4 Preclinical
CHEMBL3719368 8.2 IC50 6.3 Preclinical
CHEMBL3715966 8.15 IC50 7.1 Preclinical
CHEMBL3716872 8.14 IC50 7.3 Preclinical
CHEMBL3718546 8.12 IC50 7.5 Preclinical
CHEMBL3717607 8.03 IC50 9.4 Preclinical
CHEMBL3718343 7.98 IC50 10.5 Preclinical
CHEMBL3717961 7.96 IC50 11.0 Preclinical
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
0
6.0
0
6.5
0
7.0
32
7.5
6
8.0
2
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

1
Total Assays
40
Tested Compounds
1
Assay Types
Functional — 1 assays, 40 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 1 40 7.9

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine