T1R2/T1R3 · PROTEIN COMPLEX · Homo sapiens
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt Q8TE23. Use UniProt Q8TE23 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q8TE23 as the stable identity anchor, then attach disease evidence before program review.
Taste receptor type 1 member 2
Review this target as T1R2/T1R3, mapped to UniProt Q8TE23. ChEMBL maps the protein component as Taste receptor type 1 member 2. Sequence length is 839 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats T1R2/T1R3 as ChEMBL target CHEMBL3832642, mapped to UniProt Q8TE23. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | T1R2/T1R3 |
| Target Type | PROTEIN COMPLEX |
| Organism | Homo sapiens |
| UniProt | Q8TE23 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Taste receptor type 1 member 2 |
| UniProt Accession | Q8TE23 |
| Component Type | Protein |
| Sequence Length | 839 aa |
Taste receptor type 1 member 2
Review this target as T1R2/T1R3, mapped to UniProt Q8TE23. ChEMBL maps the protein component as Taste receptor type 1 member 2. Sequence length is 839 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3717758 | 6.85 | EC50 | 140.0 | Preclinical |
| CHEMBL3719110 | 6.72 | EC50 | 190.0 | Preclinical |
| CHEMBL3716208 | 6.68 | EC50 | 210.0 | Preclinical |
| CHEMBL3715898 | 6.38 | EC50 | 420.0 | Preclinical |
| CHEMBL3717965 | 6.35 | EC50 | 450.0 | Preclinical |
| CHEMBL3716884 | 6.31 | EC50 | 490.0 | Preclinical |
| CHEMBL3717355 | 6.29 | EC50 | 510.0 | Preclinical |
| CHEMBL3718788 | 6.2 | EC50 | 630.0 | Preclinical |
| CHEMBL3718675 | 6.19 | EC50 | 650.0 | Preclinical |
| CHEMBL3716322 | 6.15 | EC50 | 710.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 14 | 1 | 4.5 |
| protein complex format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 10 | 175 | 5.7 |