4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) · SINGLE PROTEIN · Staphylococcus aureus (strain MW2)
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As of 2026-09-14Protein identity stays anchored to UniProt Q8NUQ6. Use UniProt Q8NUQ6 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q8NUQ6 as the stable identity anchor, then attach disease evidence before program review.
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)
Review this target as 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming), mapped to UniProt Q8NUQ6. Sequence length is 502 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) as ChEMBL target CHEMBL3832958, mapped to UniProt Q8NUQ6. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) |
| Target Type | SINGLE PROTEIN |
| Organism | Staphylococcus aureus (strain MW2) |
| UniProt | Q8NUQ6 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) |
| UniProt Accession | Q8NUQ6 |
| Component Type | Protein |
| Sequence Length | 502 aa |
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)
Review this target as 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming), mapped to UniProt Q8NUQ6. Sequence length is 502 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3814424 | 8.47 | IC50 | 3.4 | Preclinical |
| CHEMBL4284707 | 8.43 | IC50 | 3.7 | Preclinical |
| CHEMBL4288408 | 8.26 | IC50 | 5.5 | Preclinical |
| CHEMBL4278050 | 8.23 | IC50 | 5.9 | Preclinical |
| CHEMBL3827961 | 8.15 | IC50 | 7.1 | Preclinical |
| CHEMBL4086008 | 8.1 | IC50 | 7.9 | Preclinical |
| CHEMBL4101749 | 8.1 | IC50 | 8.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 8 | 7 | 8.2 |