Cytoplasmic tyrosine-protein kinase BMX · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P51813. Use UniProt P51813 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P51813 as the stable identity anchor, then attach disease evidence before program review.
Cytoplasmic tyrosine-protein kinase BMX
Review this target as Cytoplasmic tyrosine-protein kinase BMX, mapped to UniProt P51813. Sequence length is 675 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Cytoplasmic tyrosine-protein kinase BMX as ChEMBL target CHEMBL3834, mapped to UniProt P51813. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Cytoplasmic tyrosine-protein kinase BMX |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P51813 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Cytoplasmic tyrosine-protein kinase BMX |
| UniProt Accession | P51813 |
| Component Type | Protein |
| Sequence Length | 675 aa |
Cytoplasmic tyrosine-protein kinase BMX
Review this target as Cytoplasmic tyrosine-protein kinase BMX, mapped to UniProt P51813. Sequence length is 675 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1643976 | 9.4 | IC50 | 0.4 | Preclinical |
| CHEMBL1873475 | 9.4 | IC50 | 0.4 | Approved |
| CHEMBL3647964 | 9.4 | IC50 | 0.4 | Preclinical |
| CHEMBL5757288 | 9.39 | IC50 | 0.41 | Preclinical |
| CHEMBL5189379 | 9.22 | IC50 | 0.6 | Preclinical |
| CHEMBL3936761 | 9.21 | IC50 | 0.62 | Approved |
| CHEMBL3290148 | 9.15 | IC50 | 0.71 | Preclinical |
| CHEMBL3182647 | 9.1 | IC50 | 0.8 | Preclinical |
| CHEMBL4560385 | 9.05 | IC50 | 0.9 | Preclinical |
| CHEMBL288441 | 9.0 | IC50 | 1.0 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 351 | 204 | 7.4 |
| assay format | 76 | 89 | 6.8 |
| cell-based format | 47 | 55 | 6.7 |
| subcellular format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 10 | 2 | 6.3 |
| assay format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 3 | 1 | 7.4 |
| cell-based format | 1 | 0 | — |
| single protein format | 1 | 2 | 9.3 |