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Target Snapshot

CHEMBL3846 Target Snapshot

3',5'-cyclic-AMP phosphodiesterase 4D · SINGLE PROTEIN · Mus musculus

1Compounds
1Assays
0Approved Drugs
1.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt Q01063. Use UniProt Q01063 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q01063 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats 3',5'-cyclic-AMP phosphodiesterase 4D as ChEMBL target CHEMBL3846, mapped to UniProt Q01063. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
3',5'-cyclic-AMP phosphodiesterase 4D
SINGLE PROTEIN · Mus musculus
As of 2026-09-14
ChEMBL target ID
CHEMBL3846
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
Q01063
3',5'-cyclic-AMP phosphodiesterase 4D
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

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Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether 3',5'-cyclic-AMP phosphodiesterase 4D is the right protein anchor across sources, using UniProt Q01063 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein Label3',5'-cyclic-AMP phosphodiesterase 4D
UniProt AccessionQ01063
Component TypeProtein
Sequence Length747 aa

3',5'-cyclic-AMP phosphodiesterase 4D

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as 3',5'-cyclic-AMP phosphodiesterase 4D, mapped to UniProt Q01063. Sequence length is 747 aa.

Mapped IDQ01063
Review name3',5'-cyclic-AMP phosphodiesterase 4D
OrganismMus musculus
Assay Mix

Activity Type Distribution

IC501.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL4209111 6.89 IC50 130.0 Preclinical
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
0
6.0
1
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

1
Total Assays
1
Tested Compounds
1
Assay Types
Binding — 1 assays, 1 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 1 1 6.9

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine