5'-AMP-activated protein kinase subunit beta-1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q9Y478. Use UniProt Q9Y478 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9Y478 as the stable identity anchor, then attach disease evidence before program review.
5'-AMP-activated protein kinase subunit beta-1
Review this target as 5'-AMP-activated protein kinase subunit beta-1, mapped to UniProt Q9Y478. Sequence length is 270 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats 5'-AMP-activated protein kinase subunit beta-1 as ChEMBL target CHEMBL3847, mapped to UniProt Q9Y478. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | 5'-AMP-activated protein kinase subunit beta-1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9Y478 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | 5'-AMP-activated protein kinase subunit beta-1 |
| UniProt Accession | Q9Y478 |
| Component Type | Protein |
| Sequence Length | 270 aa |
5'-AMP-activated protein kinase subunit beta-1
Review this target as 5'-AMP-activated protein kinase subunit beta-1, mapped to UniProt Q9Y478. Sequence length is 270 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2385579 | 7.4 | IC50 | 39.9 | Preclinical |
| CHEMBL2385600 | 7.36 | IC50 | 44.0 | Preclinical |
| CHEMBL2385586 | 7.09 | IC50 | 82.0 | Preclinical |
| CHEMBL478629 | 6.63 | IC50 | 234.6 | Preclinical |
| CHEMBL2205426 | 6.48 | Ki | 333.0 | Preclinical |
| CHEMBL3891221 | 6.4 | IC50 | 400.0 | Preclinical |
| CHEMBL3986871 | 6.38 | IC50 | 420.0 | Preclinical |
| CHEMBL3668018 | 6.28 | IC50 | 527.0 | Preclinical |
| CHEMBL2385596 | 6.02 | IC50 | 960.0 | Preclinical |
| CHEMBL513147 | 5.95 | IC50 | 1122.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 22 | 18 | 6.1 |
| cell-based format | 3 | 4 | 5.6 |
| subcellular format | 1 | 2 | 5.8 |