Fusion glycoprotein F0 · SINGLE PROTEIN · Human respiratory syncytial virus A (strain A2)
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As of 2026-09-13Fusion glycoprotein F0 shows late clinical disease relevance led by Respiratory Syncytial Virus Infection. 2 linked drugs keep the current disease frame grounded. Protein identity stays anchored to UniProt P03420. Start with Respiratory Syncytial Virus Infection, then reuse UniProt P03420 as the stable protein anchor across project notes and exports.
Start with Respiratory Syncytial Virus Infection, then reuse UniProt P03420 as the stable protein anchor across project notes and exports.
Fusion glycoprotein F0 shows late clinical disease relevance led by Respiratory Syncytial Virus Infection. 2 linked drugs remain visible in the same block.
Start review with Respiratory Syncytial Virus Infection because it currently carries late clinical support. Linked drugs include PRESATOVIR, SUPTAVUMAB. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.
Disease source · ChEMBL drug mechanism + indication proxyFusion glycoprotein F0
Review this target as Fusion glycoprotein F0, mapped to UniProt P03420. Sequence length is 574 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Fusion glycoprotein F0 as ChEMBL target CHEMBL3856166, mapped to UniProt P03420. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
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Start here when your first question is whether Fusion glycoprotein F0 is the right protein anchor across sources, using UniProt P03420 as the stable mapping.
Jump to Protein ContextUse this block first when you need to confirm why Respiratory Syncytial Virus Infection is currently framed as late clinical support. It currently carries 2 linked drugs in the same disease frame.
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Open Review-ready CardVerify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | Fusion glycoprotein F0 |
| Target Type | SINGLE PROTEIN |
| Organism | Human respiratory syncytial virus A (strain A2) |
| UniProt | P03420 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Fusion glycoprotein F0 |
| UniProt Accession | P03420 |
| Component Type | Protein |
| Sequence Length | 574 aa |
Fusion glycoprotein F0
Review this target as Fusion glycoprotein F0, mapped to UniProt P03420. Sequence length is 574 aa.
Open Targets-ready disease context using the current target-indication evidence contract.
Fusion glycoprotein F0 shows late clinical disease relevance led by Respiratory Syncytial Virus Infection.
Start review with Respiratory Syncytial Virus Infection because it currently carries late clinical support. Linked drugs include PRESATOVIR, SUPTAVUMAB. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4740044 | 9.57 | EC50 | 0.27 | Preclinical |
| CHEMBL4750881 | 9.48 | EC50 | 0.33 | Preclinical |
| CHEMBL4469438 | 9.4 | IC50 | 0.4 | Preclinical |
| CHEMBL4747540 | 9.33 | EC50 | 0.47 | Preclinical |
| CHEMBL4878302 | 9.3 | IC50 | 0.5 | Preclinical |
| CHEMBL4755451 | 9.19 | EC50 | 0.64 | Preclinical |
| CHEMBL4876200 | 9.16 | IC50 | 0.69 | Preclinical |
| CHEMBL4872095 | 9.15 | IC50 | 0.7 | Preclinical |
| CHEMBL4746199 | 9.13 | EC50 | 0.74 | Preclinical |
| CHEMBL4765002 | 9.11 | EC50 | 0.77 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 7 | 48 | 8.3 |
| single protein format | 1 | 4 | 9.1 |