Nuclear factor of activated T-cells, cytoplasmic 1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt O95644. Use UniProt O95644 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O95644 as the stable identity anchor, then attach disease evidence before program review.
Nuclear factor of activated T-cells, cytoplasmic 1
Review this target as Nuclear factor of activated T-cells, cytoplasmic 1, mapped to UniProt O95644. Sequence length is 943 aa.
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This review treats Nuclear factor of activated T-cells, cytoplasmic 1 as ChEMBL target CHEMBL3876, mapped to UniProt O95644. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Nuclear factor of activated T-cells, cytoplasmic 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | O95644 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Nuclear factor of activated T-cells, cytoplasmic 1 |
| UniProt Accession | O95644 |
| Component Type | Protein |
| Sequence Length | 943 aa |
Nuclear factor of activated T-cells, cytoplasmic 1
Review this target as Nuclear factor of activated T-cells, cytoplasmic 1, mapped to UniProt O95644. Sequence length is 943 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4064316 | 6.51 | EC50 | 310.0 | Preclinical |
| CHEMBL4105629 | 5.8 | EC50 | 1590.0 | Preclinical |
| CHEMBL4077010 | 5.66 | EC50 | 2210.0 | Preclinical |
| CHEMBL4084955 | 5.53 | EC50 | 2980.0 | Preclinical |
| CHEMBL5174163 | 5.35 | IC50 | 4500.0 | Preclinical |
| CHEMBL4079572 | 5.32 | EC50 | 4800.0 | Preclinical |
| CHEMBL4098505 | 5.31 | EC50 | 4850.0 | Preclinical |
| CHEMBL4075648 | 5.28 | EC50 | 5310.0 | Preclinical |
| CHEMBL4091320 | 5.16 | EC50 | 6900.0 | Preclinical |
| CHEMBL4095674 | 5.16 | EC50 | 6960.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 14 | 3 | 5.0 |
| assay format | 1 | 14 | 5.2 |