Metabotropic glutamate receptor 7 · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt P35400. Use UniProt P35400 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P35400 as the stable identity anchor, then attach disease evidence before program review.
Metabotropic glutamate receptor 7
Review this target as Metabotropic glutamate receptor 7, mapped to UniProt P35400. Sequence length is 915 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Metabotropic glutamate receptor 7 as ChEMBL target CHEMBL3879, mapped to UniProt P35400. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Metabotropic glutamate receptor 7 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P35400 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Metabotropic glutamate receptor 7 |
| UniProt Accession | P35400 |
| Component Type | Protein |
| Sequence Length | 915 aa |
Metabotropic glutamate receptor 7
Review this target as Metabotropic glutamate receptor 7, mapped to UniProt P35400. Sequence length is 915 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL595170 | 7.92 | IC50 | 12.0 | Preclinical |
| CHEMBL595840 | 7.7 | IC50 | 20.0 | Preclinical |
| CHEMBL595402 | 7.68 | IC50 | 21.0 | Preclinical |
| CHEMBL399602 | 7.66 | IC50 | 22.0 | Preclinical |
| CHEMBL399603 | 7.58 | IC50 | 26.0 | Preclinical |
| CHEMBL593489 | 7.58 | IC50 | 26.0 | Preclinical |
| CHEMBL592954 | 7.54 | IC50 | 29.0 | Preclinical |
| CHEMBL594223 | 7.51 | IC50 | 31.0 | Preclinical |
| CHEMBL5271313 | 7.37 | EC50 | 42.66 | Preclinical |
| CHEMBL595825 | 7.29 | IC50 | 51.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 40 | 195 | 5.7 |
| assay format | 9 | 4 | 4.4 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 18 | 17 | 6.2 |
| cell-based format | 14 | 7 | 6.2 |
| cell membrane format | 2 | 2 | 6.9 |
| assay format | 1 | 3 | — |