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Target Snapshot

CHEMBL3879801 Target Snapshot

NON-PROTEIN TARGET · NON-MOLECULAR

98,546Compounds
37,704Assays
363Approved Drugs
98,523.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats NON-PROTEIN TARGET as ChEMBL target CHEMBL3879801. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
NON-PROTEIN TARGET
NON-MOLECULAR
As of 2026-09-13
ChEMBL target ID
CHEMBL3879801
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether NON-PROTEIN TARGET still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

Jump to Disease Context
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Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelNON-PROTEIN TARGET
UniProt AccessionN/A

NON-PROTEIN TARGET

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as NON-PROTEIN TARGET.

Review nameNON-PROTEIN TARGET
Clinical Profile

Clinical Phase Distribution

363
Approved
113
Phase III
195
Phase II
53
Phase I
2
Phase 0.5
Assay Mix

Activity Type Distribution

IC5088,098.0
KI53.0
EC5010,345.0
KD27.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL3891600 11.0 EC50 0.01 Preclinical
CHEMBL3892720 11.0 EC50 0.01 Preclinical
CHEMBL3915742 11.0 EC50 0.01 Preclinical
CHEMBL3919651 11.0 EC50 0.01 Preclinical
CHEMBL3960757 11.0 EC50 0.01 Preclinical
CHEMBL2158596 11.0 IC50 0.01 Preclinical
CHEMBL1823147 11.0 IC50 0.01 Preclinical
CHEMBL1254992 11.0 IC50 0.01 Preclinical
CHEMBL846 11.0 IC50 0.01 Approved
CHEMBL67 11.0 IC50 0.01 Preclinical
Distribution

pChEMBL Value Distribution

13345
5.0
9730
5.5
7104
6.0
4575
6.5
3478
7.0
2424
7.5
1872
8.0
917
8.5
519
9.0
225
9.5
pChEMBL
Approved Drugs

Approved Drugs

MOMELOTINIB
CHEMBL1078178
Approved 2023
QUIZARTINIB
CHEMBL576982
Approved 2023
PACRITINIB
CHEMBL2035187
Approved 2022
BRINCIDOFOVIR
CHEMBL203321
Approved 2021
INFIGRATINIB PHOSPHATE
CHEMBL1834657
Approved 2021
ARTESUNATE
CHEMBL361497
Approved 2020
LONAFARNIB
CHEMBL298734
Approved 2020
NIFURTIMOX
CHEMBL290960
Approved 2020
SELUMETINIB
CHEMBL1614701
Approved 2020
ENTRECTINIB
CHEMBL1983268
Approved 2019
FEDRATINIB
CHEMBL1287853
Approved 2019
CANNABIDIOL
CHEMBL190461
Approved 2018
TALAZOPARIB
CHEMBL3137320
Approved 2018
DUVELISIB
CHEMBL3039502
Approved 2018
NIRAPARIB
CHEMBL1094636
Approved 2017
NERATINIB
CHEMBL180022
Approved 2017
BRIGATINIB
CHEMBL3545311
Approved 2017
RUCAPARIB
CHEMBL1173055
Approved 2016
PALBOCICLIB
CHEMBL189963
Approved 2015
PANOBINOSTAT
CHEMBL483254
Approved 2015
TENOFOVIR ALAFENAMIDE
CHEMBL2107825
Approved 2015
ALECTINIB
CHEMBL1738797
Approved 2015
IDEBENONE
CHEMBL252556
Approved 2015
COBIMETINIB
CHEMBL2146883
Approved 2015
OLAPARIB
CHEMBL521686
Approved 2014
NINTEDANIB
CHEMBL502835
Approved 2014
BELINOSTAT
CHEMBL408513
Approved 2014
CERITINIB
CHEMBL2403108
Approved 2014
IDELALISIB
CHEMBL2216870
Approved 2014
AFATINIB
CHEMBL1173655
Approved 2013
POMALIDOMIDE
CHEMBL43452
Approved 2013
TRAMETINIB
CHEMBL2103875
Approved 2013
PONATINIB
CHEMBL1171837
Approved 2012
VISMODEGIB
CHEMBL473417
Approved 2012
CABOZANTINIB S-MALATE
CHEMBL2103868
Approved 2012
AXITINIB
CHEMBL1289926
Approved 2012
CABOZANTINIB
CHEMBL2105717
Approved 2012
BOSUTINIB
CHEMBL288441
Approved 2012
TOFACITINIB
CHEMBL221959
Approved 2012
CRIZOTINIB
CHEMBL601719
Approved 2011
VEMURAFENIB
CHEMBL1229517
Approved 2011
ROFLUMILAST
CHEMBL193240
Approved 2010
ERIBULIN
CHEMBL1683590
Approved 2010
ERIBULIN MESYLATE
CHEMBL1683544
Approved 2010
FINGOLIMOD
CHEMBL314854
Approved 2010
CARFILZOMIB
CHEMBL451887
Approved 2009
PRALATREXATE
CHEMBL1201746
Approved 2009
OMACETAXINE MEPESUCCINATE
CHEMBL46286
Approved 2009
ROMIDEPSIN
CHEMBL343448
Approved 2009
DABIGATRAN ETEXILATE
CHEMBL539697
Approved 2008
Source · ChEMBL 36 via Core Engine