Shiga toxin subunit A · SINGLE PROTEIN · Shigella dysenteriae
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As of 2026-09-14Protein identity stays anchored to UniProt Q9FBI2. Use UniProt Q9FBI2 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9FBI2 as the stable identity anchor, then attach disease evidence before program review.
Shiga toxin subunit A
Review this target as Shiga toxin subunit A, mapped to UniProt Q9FBI2. Sequence length is 315 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Shiga toxin subunit A as ChEMBL target CHEMBL3879822, mapped to UniProt Q9FBI2. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Shiga toxin subunit A |
| Target Type | SINGLE PROTEIN |
| Organism | Shigella dysenteriae |
| UniProt | Q9FBI2 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Shiga toxin subunit A |
| UniProt Accession | Q9FBI2 |
| Component Type | Protein |
| Sequence Length | 315 aa |
Shiga toxin subunit A
Review this target as Shiga toxin subunit A, mapped to UniProt Q9FBI2. Sequence length is 315 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3963596 | 6.14 | Kd | 716.0 | Preclinical |
| CHEMBL3935227 | 5.58 | IC50 | 2630.0 | Preclinical |
| CHEMBL3933587 | 5.49 | Ki | 3210.0 | Preclinical |
| CHEMBL3939786 | 5.47 | Ki | 3360.0 | Preclinical |
| CHEMBL2375419 | 5.39 | Ki | 4100.0 | Preclinical |
| CHEMBL3917910 | 5.3 | Ki | 5000.0 | Preclinical |
| CHEMBL1253710 | 5.22 | Ki | 5960.0 | Preclinical |
| CHEMBL3935227 | 5.17 | Ki | 6690.0 | Preclinical |
| CHEMBL250859 | 5.11 | IC50 | 7700.0 | Preclinical |
| CHEMBL3963596 | 5.1 | IC50 | 7960.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 5 | 6 | 5.1 |
| single protein format | 5 | 20 | 4.9 |