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Target Snapshot

CHEMBL3879858 Target Snapshot

RNA-binding protein FXR1 · SINGLE PROTEIN · Homo sapiens

5Compounds
6Assays
0Approved Drugs
2.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Protein identity stays anchored to UniProt P51114. Use UniProt P51114 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt P51114 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats RNA-binding protein FXR1 as ChEMBL target CHEMBL3879858, mapped to UniProt P51114. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
RNA-binding protein FXR1
SINGLE PROTEIN · Homo sapiens
As of 2026-09-13
ChEMBL target ID
CHEMBL3879858
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
UniProt accession
P51114
RNA-binding protein FXR1
UniProt accession via ChEMBL component mapping As of 2026-09-13
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether RNA-binding protein FXR1 is the right protein anchor across sources, using UniProt P51114 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelRNA-binding protein FXR1
UniProt AccessionP51114
Component TypeProtein
Sequence Length621 aa

RNA-binding protein FXR1

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as RNA-binding protein FXR1, mapped to UniProt P51114. Sequence length is 621 aa.

Mapped IDP51114
Review nameRNA-binding protein FXR1
OrganismHomo sapiens
Assay Mix

Activity Type Distribution

KD2.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL5653589 8.71 Kd 1.973 Preclinical
CHEMBL3752910 8.02 Kd 9.572 Preclinical
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
0
6.0
0
6.5
0
7.0
0
7.5
1
8.0
1
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

6
Total Assays
2
Tested Compounds
1
Assay Types
Binding — 6 assays, 2 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 6 2 8.4

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine